Prion Diseases in Animals

نویسندگان

  • Seong Soo An
  • Kuntaek Lim
  • Young Chul Youn
  • Eva Bagyinszky
  • Christiane Segarra
  • Sungmin Kang
  • Takahashi Yokoyama
  • Joliette Coste
  • SangYun Kim
  • Nishandan Yogasingam
  • Gordon Mitchell
  • Aru Balachandran
  • Oliver Bannach
  • Elke Reinartz
  • Detlev Riesner
  • Dieter Willbold
  • Eva Birkmann
  • Florica Barbuceanu
  • Cristina Diaconu
  • Stefania Raita
  • Mihai Turcitu
  • Lidia Chitimia
  • Gabriel Predoi
  • Paula Saá
  • Oksana Yakovleva
  • Jorge de Castro
  • Larisa Cervenakova
  • Alan Elder
  • Davin Henderson
  • Anca Selariu
  • Amy Nalls
  • Byron Caughey
  • Richard Bessen
  • Jason Bartz
  • Candace Mathiason
  • John Paul J. Glaves
  • Nathalie Daude
  • David S. Wishart
  • David Westaway
  • Brian D. Sykes
  • M. Heather W. Greenlee
  • Jodi D. Smith
  • Justin J. Greenlee
  • Laura L. Hoon-Hanks
  • Nicholas J. Haley
  • Scott Carver
  • Byron Caughey
  • Edward A. Hoover
  • Jorg G. Jacobs
  • Frédéric Lantier
  • O. Andreoletti
  • Francis Barillet
  • Cristina Acin
  • Wilfred Goldmann
  • T. Sklaviadis
  • Christine Fast
  • Pier Luigi Acutis
  • Stéphanie Simon
  • Juan Maria Torres
  • Lucien V Keulen
  • Alex Bossers
  • Lorenzo Gonzalez
  • Romolo Nonno
  • Jan Langeveld
  • Theodore R. John
  • Hermann M. Schätzl
  • Sabine Gilch
  • Aaron D. Lehmkuhl
  • Bruce V. Thomsen
  • Katherine I. O’Rourke
  • Aru Balachandran
  • Mark Hall
  • Daniele Macrì
  • Maurizio Bivona
  • Stefano Reale
  • Simona Calderone
  • Giuseppe Rapisarda
  • Fabrizio Vitale
  • Daniela Meloni
  • Maria C. Cavarretta
  • Daniela Loprevite
  • Danilo Pitardi
  • Cristina Bona
  • Elena Bozzetta
  • Christoph W. Sensen
  • Anne Balkema-Buschmann
  • Julia Beck
  • Bertram Brenig
  • Robert B. Church
  • Paul M. Gordon
  • Martin H. Groschup
  • Ekkehard Schütz
  • Maria Sensen
  • Deepthi T. Thomas Kannanayakal
  • Howard B. Urnovitz
  • Xinli Tang
  • Debbie McKenzie
  • Judd Aiken
  • A.C. Wyckoff
  • Nathan Galloway
  • Jenny Powers
  • Terry Spraker
  • Crystal M. Reid
  • Bruce Pulford
  • Nick Haley
  • Kurt VerCauteren
  • Mark Zabel
  • Sandor Dudas
  • Catherine Graham
  • Bob Hills
  • Stefanie Czub
  • Tiejun T. Gao
  • Raynald Lee
  • Shu S. Li
  • Darren Achtymichuk
  • Catherine Graham
  • Stefanie Czub
  • Wilfred Goldmann
  • Cristina Acin
  • Pier Luigi Acutis
  • Umberto Agrimi
  • Olivier Andreoletti
  • Francis Barillet
  • Cynthia H. Panagiotidis
  • Simone Peletto
  • Theodoros Sklaviadis
  • Gabriele Vaccari
  • Jan Langeveld
  • Alex Bossers
  • Kristen Marciniuk
  • Ryan Taschuk
  • Pekka Maattanen
  • Dean Airey
  • Neil Cashman
  • Andrew Potter
  • Philip Griebel
  • Scott Napper
  • Hernan Ortegon
  • Eva Chow
  • Christa Coetser
  • Gerald Hauer
  • Margo Pybus
  • Ana M. Ulmer-Franco
  • Laura Pirisinu
  • Elena Esposito
  • Gabriele Vaccari
  • Claudia D’Agostino
  • Stefano Marcon
  • Michele A. Di Bari
  • Frederic Lantier
  • Cristina Acin
  • Juan M. Torres
  • Olivier Andreoletti
  • Wilfred Goldmann
  • Theodoros Sklaviadis
  • Christine Fast
  • Pier L. Acutis
  • Stephanie Simon
  • Jan Langeveld
  • Alex Bossers
  • Umberto Agrimi
  • Romolo Nonno
  • Suresh Tikoo
  • Neil Cashman
  • Rosa Xicohtencatl
  • Paula Stewart
  • Wilfred Goldmann
  • Fabiola Rodriguez
  • Esteban Aquino
  • Felix Aquino
  • Ramses Cuautle
  • Laura Mendoza
  • Raymundo Avila
  • Andres Rojas
  • Aleksander A. Yegorov
  • Sergey S. Rybakov
  • Asya V. Borisova
  • Andrey V. Pavlov
  • Heather Bender
  • Noelle Noyes
  • Mark Zabel
  • Larisa Cervenakova
  • Oksana Yakovleva
  • Irina Vasilyeva
  • Jorge De Castro
  • Paula Saa
  • Judith Kelleher-Andersson
  • Pedro Piccardo
  • Christine Fast
  • Patricia Berthon
  • Kerstin Tauscher
  • Isabelle Lantier
  • Susanne Freyse
  • Christelle Rossignol
  • Anne Balkema-Buschmann
  • Herve Le Roux
  • Francis Barillet
  • Olivier Andreoletti
  • Alex Bossers
  • Jan Langeveld
  • Juan M. Torres
  • Juan C. Espinosa
  • Patricia Aguilar
  • Lorenzo Gonzalez
  • Martin H. Groschup
  • Wilfred Goldmann
  • Frederic Lantier
  • Seyed Ali Goldansaz
  • Dagnachew Hailamariam
  • Fozia Saleem
  • Nathalie Daude
  • David Wishart
  • David Westaway
  • Burim N. Ametaj
  • Dagnachew Hailemariam
  • Seyed Ali Goldansaz
  • Fozia Saleem
  • Nathalie Daude
  • David Wishart
  • David Westaway
  • Burim N. Ametaj
  • Fozia Saleem
  • David Wishart
  • Rie Hasebe
  • Hiroyuki Kabuki
  • Yusuke Takahashi
  • Akio Suzuki
  • Takeshi Yamasaki
  • Motohiro Horiuchi
  • Allison Kraus
  • Brent Race
  • Katie Phillips
  • Bradley Groveman
  • Michael Kurnellas
  • Jonathan B. Rothbard
  • Lawrence Steinman
  • Byron Caughey
  • Geraldina Riccardi
  • Juan M. Torres
  • Wilfred Goldmann
  • Christine Fast
  • Pier L. Acutis
  • Stephanie Simon
  • John Spiropoulos
  • Jan Langeveld
  • Alex Bossers
  • Hyun Joo Sohn
  • Yoon Hee Lee
  • Min Jeoing Kim
  • Hyo Jin Kim
  • Won Young Lee
  • Hoo Chang Park
  • Kyung Je Park
  • In Soo Cho
  • Thomas Wisniewski
  • Candace Mathiason
  • Daniel K. Peyser
  • Krystal Herline
  • Amy Nalls
  • Kelly Anderson
  • Veronica Estevez
  • Lucia Yim
  • David Brown
  • Jose A. Chabalogoity
  • Edward A. Hoover
  • Fernando Goni
  • Takehiro Nakagaki
  • Noriyuki Nishida
  • Ryuichiro Atarashi
  • Pamela Banser
  • Camilo D. Velasquez
  • Charlie Mays
  • Valerie Sim
  • Allen Herbst
  • Jason R. Hollister
  • Kil Sun Lee
  • Gerald S. Baron
  • Jifeng Bian
  • Glenn C. Telling
  • Brenda F. Canine
  • Richard Bennett
  • Andrea Grindeland
  • Ranjit Giri
  • Inyoul Lee
  • Leroy Hood
  • George A. Carlson
  • Christina M. Carlson
  • Jay R. Schneider
  • Jamie K. Wiepz
  • Crystal L. Meyerett-Reid
  • Mark D. Zabel
  • Joel A. Pedersen
  • Dennis M. Heisey
  • Christopher J. Johnson
  • James A. Carroll
  • Brent Race
  • Katie Phillips
  • Bruce Chesebro
  • Young Pyo Choi
  • Suzette A. Priola
  • Camilo Duque-Velasquez
  • Allen Herbst
  • Chiye Kim
  • Chad Johnson
  • Judd Aiken
  • Debbie McKenzie
  • Analía Elisei
  • Natalia G. Porta
  • Gabriel B. Pinto
  • Thomas Wisniewski
  • Fernando Goñi
  • Karina G. Trono
  • Dana C. Hill
  • Breanna Smith
  • Mark D. Zabel
  • Hae-Eun Kang
  • Sehun Kim
  • Sang-Gyun Kang
  • Chiye Kim
  • Anthony E. Kincaid
  • Melissa Clouse
  • Albert Lorenzo
  • Jason C. Bartz
  • Kamilla Kosciuczyk
  • Lise Lamoureux
  • Margot Plews
  • Sharon L. Simon
  • J D. Knox
  • Sharon Simon
  • Brooks Waitt
  • David Knox
  • Kentaro Masujin
  • Naoko Tabeta
  • Ritsuko Miwa
  • Kohtaro Miyazawa
  • Hiroyuki Okada
  • Shirou Mohri
  • Takashi Yokoyama
  • Charles E. Mays
  • Chae Kim
  • Tracy Haldiman
  • Jacques van der Merwe
  • Agnes Lau
  • Michele A. Di Bari
  • Umberto Agrimi
  • Qingzhong Kong
  • Jan Langeveld
  • David Westaway
  • Jiri G. Safar
  • Camilo Duque Velasquez
  • Gordon E. Mitchell
  • Antanas Staskevicius
  • Patricia Shaffer
  • Masanori Morita
  • Miyuki Yamamoto
  • Tetsuyuki Kitamoto
  • Juan F. Munoz-Gutierrez
  • David A. Schneider
  • Timothy V. Baszler
  • James B. Stanton
  • Amy V. Nalls
  • Davis Seelig
  • Susan Kraft
  • Kevin Carnes
  • Kelly Anderson
  • Jeanette Hayes-Klug
  • Dan Sturdevant
  • Kimberly Meade-White
  • Roger A. Moore
  • Berta Puig
  • Hermann C. Altmeppen
  • Susanne Krasemann
  • Karima Chakroun
  • Ulrike Resenberger
  • Jörg Tatzelt
  • Markus Glatzel
  • Alejandra H. Rangel
  • James Striebel
  • Claudine R. Raymond
  • Gordon Mitchell
  • Antanas Staskevicius
  • Thierry Baron
  • Aru Balachandran
  • Dong Seob Tark
  • Yoon Hee Lee
  • Hyun Joo Sohn
  • Min Jeoing Kim
  • Hyo Jin Kim
  • Kyung Je Park
  • Won Young Lee
  • Eun Im Yoon
  • Dong Seob Tark
  • Young Pyo Choi
  • In Soo Cho
  • Aru Balachandran
  • Vickery M. Christopher
  • Leigh Thorne
  • Katy E. Beck
  • Marion M. Simmons
  • John Spiropoulos
  • James F. Striebel
  • Melissa Pathmajeyan
  • Alejandra Rangel
  • Jacques Q. van der Merwe
  • Glenn C. Telling
  • Catherine Vrentas
  • Justin Greenlee
  • Thierry Baron
  • Maria Caramelli
  • Stefanie Czub
  • Eric Nicholson
  • Jianmin Yang
  • Tammy Pickles
  • Sandor Dudas
  • Catherine Graham
  • Stefanie Czub
  • Kazuo Kasai
  • Yoshifumi Iwamaru
  • Morikazu Imamura
  • Alexandra R. Chesney
  • Chad J. Johnson
  • Joel A. Pedersen
  • Clare E. Hoover
  • Michael J. Oglesbee
  • Mark D. Zabel
  • Zuzana Krejciova
  • Justin Greenlee
  • Robert A. Kunkle
  • Jodi D. Smith
  • Nicholas J. Haley
  • Davin Henderson
  • Edward A. Hoover
  • Christen B. Smith
  • Michael D. Samuel
  • Sandra J. Pritzkow
  • Rodrigo Morales
  • Fabio Moda
  • Claudio Soto
  • Jay D. Rasmussen
  • Brandon H. Gilroyed
  • Tim Reuter
  • Sandor Dudas
  • Catherine Graham
  • Norman F. Neumann
  • Aru Balachandran
  • Stefanie Czub
  • Nat N. Kav
  • Tim A. McAllister
  • Yuichi Matsuura
  • Yukiko Ishikawa
  • Xiao Bo
  • Yuichi Murayama
  • Takashi Yokoyama
  • Robert A. Somerville
  • Tetsuyuki Kitamoto
  • Shirou Mohri
چکیده

Previously, Multimer Detection System (MDS) detected scrapie infected lambs of 8 mo age at pre-clinical stage in comparison with the normal controls. Above lamb were born from scrapie infected parent sheep (VRQ/VRQ). Here, MDS was challenged twice blindly with scrapie sheep blood samples from pre-clinical stages. These sheep showed no symptoms and they died of scrapie after 24 mo or more. Both normal and pre-clinical scrapie blood samples were coded before the testing with MDS and decoded after the results. After decoding, MDS clearly differentiated all pre-clinical scrapie samples from the normal samples, except one pre-clinical sample, which was pretreated with protease digestion. MDS detected only oligomeric forms of PrP in the pool of normal prion monomers, where MDS used multimeric expression of epitopes on aggregated disease-associated prion protein, in contrast to one epitope in the cellular form. Hence, MDS differentiated scrapie infected sheep samples in pre-clinical stage from normal sheep blood samples. The sensitivity and rapidness of the MDS would be useful in an automated screening system for monitoring the human samples in ensuring the safety of blood products. In addition, MDS was implemented for Alzheimer Disease and Parkinson Disease. AD.02: Prion strain discrimination in ruminants using differential proteinase K and immunoblotting characteristics

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عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2001